Nathan A Bihlmeyer, PhD

Postdoctoral Fellow in Neurology
Massachusetts General Hospital and Harvard Medical School
MIND Informatics, Suite 200, 65 Landsdowne Street, Cambridge, MA 02139


I am a Postdoctoral Fellow in Neurology with a joint appointment at Massachusetts General Hospital (MGH) and Harvard Medical School (HMS). I am currently working on integrating multi-omic data in an effort to discover novel molecular targets in Alzheimer disease therapeutics as a part of the Massachusetts Center for Alzheimer Therapeutics Science (MassCATS) project. I work in the MassGeneral Institute for Neurodegenerative Disease (MIND) Informatics group with Dr. Tim Clark, PhD.

I have a PhD in Human Genetics from Johns Hopkins University School of Medicine focused on the genetics of electrical conduction in the heart, investigating the role of both rare and common genetic variants in humans. As a part of the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium EKG working group, I was the junior project lead supporting 23 analysts working with the Illumina ExomeChip towards finding genes that effect cardiac repolarization, and by extension risk for Sudden Cardiac Death (SCD), in a meta-analysis involving over 95,000 human subjects. My thesis mentor was Dr. Dan E Arking, PhD.

Over the five and a half years I spent in graduate school, I obtained a strong understanding of bioinformatics and managing large genotype datasets. I have worked with multiple programming languages and software packages interweaving them together, exploiting their strengths to arrive at a final bioinformatic pipeline. Then helping other analysts run that pipeline on other cohort’s data, working towards a meta-analyized final result.

I also have over three years experience in molecular biology. I have worked with the model organizes Mus musculus, Xenopus, and Arabidopsis thaliana. In additional to basic molecular biology techniques, I have experience with dissection, cryosectioning, confocal microscopy, and bimolecular fluorescence complementation.

(Updated: Thu, 01 Jun 2017 12:17:20 -0400)

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